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apalutamide will decrease the level or influence of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration of apalutamide, a strong CYP3A4 inducer, with prescription drugs which are CYP3A4 substrates may end up in lessen publicity to those medications.In case you have been getting this dr